Yi-Shi LIU 柳艺石
Jiangnan University
e-mail: liuyishi@jiangnan.edu.cn
Interests
l The regulatory of the GPI-anchored proteins biosynthesis
l Molecular cell biology
l Biomedical engineering in mammalian cells
l Protein quality control in disease and Protein homeostasis
Education and career
l 2021.01- now Jiangnan University, Assistant Professor
l 2019.07- 2020.12 Jiangnan University, Postdoc
l 2018.09-2019.09 Osaka University, Postdoc
l 2012.09-2018.06 Jiangnan University, PhD
l 2008.09-2012.06 Jiangnan University, Bachelor Degree
Honors and Awards
l 2018.06: Excellent PhD student in Jiangnan University
l 2017.10: Best reporter in Annual Graduate Research Symposium
l 2015.11: Best Poster presentation awarded in 7th ACGG Conference (Japan)
l 2012.06: Excellent graduate student in Jiangnan University
l 2010.10: National scholarship awarded in Jiangnan University
Publications
[1] Yi-Shi Liu, Yicheng Wang, Xiaoman Zhou, Linpei Zhang, Ganglong Yang, Xiao-Dong Gao, Yoshiko Murakami, Morihisa Fujita, Taroh Kinoshita; Accumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1. J Cell Biol 1 May 2023; 222 (5):e202208159
[2] Liu, Y.S., and Fujita, M. (2020). Mammalian GPI-anchor modifications and the enzymes involved. Biochem Soc Trans 48, 1129-1138.
[3] Wang, Y., Maeda, Y., Liu, Y.S., Takada, Y., Ninomiya, A., Hirata, T., Fujita, M., Murakami, Y., and Kinoshita, T. (2020). Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation. Nat Commun 11, 860.
[4] Mutumwinka, D., Zhao, S.B., Liu, Y.S., Mensah, E.O., Gao, X.D., and Fujita, M. (2018). PiggyBac-based screening identified BEM4 as a suppressor to rescue growth defects in och1-disrupted yeast cells. Biosci Biotechnol Biochem 82, 1497-1507.
[5] Kitajima, T., Xue, W., Liu, Y.S., Wang, C.D., Liu, S.S., Fujita, M., and Gao, X.D. (2018). Construction of green fluorescence protein mutant to monitor STT3B-dependent N-glycosylation. FEBS J 285, 915-928.
[6] Liu, Y.S., Guo, X.Y., Hirata, T., Rong, Y., Motooka, D., Kitajima, T., Murakami, Y., Gao, X.D., Nakamura, S., Kinoshita, T., et al. (2018). N-Glycan-dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing. J Cell Biol 217, 585-599.
[7] Matabaro, E., He, Z., Liu, Y.S., Zhang, H.J., Gao, X.D., and Fujita, M. (2017). Molecular switching system using glycosylphosphatidylinositol to select cells highly expressing recombinant proteins. Sci Rep 7, 4033.
[8] Rong, Y., Nakamura, S., Hirata, T., Motooka, D., Liu, Y.S., He, Z.A., Gao, X.D., Maeda, Y., Kinoshita, T., and Fujita, M. (2015). Genome-Wide Screening of Genes Required for Glycosylphosphatidylinositol Biosynthesis. PLoS One 10, e0138553.
