Xiaoman ZHOU 周小满

Jiangnan University

e-mail: xiaoman@jiangnan.edu.cn

Keywords: Glycan analysis; Tumor biology; Sialic acid; Proteomics

Curriculum vitae

2024.1-Today Jiangnan University, Associate Professor

2020.7- 2023.12 Jiangnan University, Postdoc.

2017.9-2020.1 Northwest University Joint Ph.D.

2015.9-2020.6 Jiangnan University, Ph.D.

2010.9-2014.6 Jiangnan University, Bachelor

ORCID

https://orcid.org/0000-0002-0270-2159

Publications

[1] Li Yuan-Bo, Wang Yan-Xiong, Yang Sen, Chen Qian-Long, Li Zhong-Hao, Liang Jun-Ge, Fan Qi-Gao, Jiang Yan-Feng, Zhou Xiaoman, Qiang Tian. Ingenious Microfluidic-Microwave integrated biosensor for cell sorting and concentration detection of mixed white blood cells and yeasts solution [J]. Chemical Engineering Journal, 2025: 159741.

[2] Zhou Xiaoman, Wang Xiuyuan, Bai Ruizhen, Li Hanjie, Hua Dong, Gao Xiao-Dong, Yang Ganglong, Liu Quan. Protein Signatures for Distinguishing Colorectal Cancer Liver Metastases from Primary Liver Cancer Using Tissue Slide Proteomics [J]. Frontiers in Bioscience-Landmark, 2024, 29(1): 3.

[3] Wang Buqing, Zhou Xiaoman, Wang Yasen, Gao Yahui, Nakanishi Hideki, Fujita Morihisa, Li Zijie. Enhancement of thermostability and expression level of Rasamsonia emersonii lipase in Pichia pastoris and its application in biodiesel production in a continuous flow reactor [J]. International Journal of Biological Macromolecules, 2024, 278: 134481.

[4] Wang Buqing, Wang Yasen, Zhou Xiaoman, Gao Xiao‐Dong, Fujita Morihisa, Li Zijie. Highly efficient expression of Rasamsonia emersonii lipase in Pichia pastoris: characterization and gastrointestinal simulated digestion in vitro [J]. Journal of the Science of Food and Agriculture, 2024, 104(9): 5603-5613.

[5] Liu Yi-Shi, Miao Yu-Long, Dou Yue, Yang Ze-Hui, Sun Wenhao, Zhou Xiaoman, Li Zijie, Hideki Nakanishi, Gao Xiao-Dong, Fujita Morihisa. Processing of N-glycans in the ER and Golgi influences the production of surface sialylated glycoRNA [J]. Glycoconjugate Journal, 2024: 1-10.

[6] Liu Yishi, Yang Zehui, Zhou Xiaoman, Li Zijie, Hideki Nakanishi. Diacylglycerol Kinases and Its Role in Lipid Metabolism and Related Diseases [J]. International Journal of Molecular Sciences, 2024, 25(23): 13207.

[7] Lin Meixuan, Xu Xiaoqiang, Zhou Xiaoman, Feng Hui, Wang Ruili, Yang Yunyun, Li Jing, Fan Ning, Jiang Yazhuo, Li Xiang. Sialylation on vesicular integrin β1 determined endocytic entry of small extracellular vesicles into recipient cells [J]. Cellular & Molecular Biology Letters, 2024, 29(1): 46.

[8] Chen Jingru, Wen Piaopiao, Tang Yu-He, Li Hanjie, Wang Zibo, Wang Xiuyuan, Zhou Xiaoman, Gao Xiao-Dong, Fujita Morihisa, Yang Ganglong. Proteome and Glycoproteome Analyses Reveal Regulation of Protein Glycosylation Site-Specific Occupancy and Lysosomal Hydrolase Maturation by N-Glycan-Dependent ER-Quality Control [J]. Journal of Proteome Research, 2024, 23(10): 4409-4421.

[9] Zhou Xiaoman*, Chi Kaijun, Zhang Chairui, Liu Quan, Yang Ganglong*. Sialylation: a cloak for tumors to trick the immune system in the microenvironment [J]. Biology, 2023, 12(6): 832.

[10] Yang Ganglong, Zuo Chenyang, Lin Yuxiang, Zhou Xiaoman, Wen Piaopiao, Zhang Chairui, Xiao Han, Jiang Meichen, Fujita Morihisa, Gao Xiao-Dong. Comprehensive proteome, phosphoproteome and kinome characterization of luminal A breast cancer [J]. Frontiers in Oncology, 2023, 13: 1127446.

[11] Xu Hui-Lin, Zhou Xiaoman, Chen Shuai, Xu Si, Li Zijie, Nakanishi Hideki, Gao Xiao-Dong. Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism [J]. Communications Biology, 2023, 6(1): 259.

[12] Wang Xiuyuan, Li Hanjie, Wang Zibo, Chen Jingru, Chen Wenyan, Zhou Xiaoman, Zhang Lina, Xu Shiqian, Gao Xiao-Dong, Yang Ganglong. Site-and Structure-Specific Glycosylation Signatures of Bovine, Caprine, Porcine, and Human Milk-Derived Extracellular Vesicles [J]. Journal of Agricultural and Food Chemistry, 2023, 71(51): 20826-20837.

[13] Liu Yi-Shi, Wang Yicheng, Zhou Xiaoman, Zhang Linpei, Yang Ganglong, Gao Xiao-Dong, Murakami Yoshiko, Fujita Morihisa, Kinoshita Taroh. Accumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1 [J]. Journal of Cell Biology, 2023, 222(5): e202208159.

[14] Chi Kaijun, Xu Huilin, Li Hanjie, Yang Ganglong, Zhou Xiaoman*, Gao Xiao-Dong*. Expression of a Siglec-Fc Protein and Its Characterization [J]. Biology, 2023, 12(4): 574.

[15] Tan Zengqi, Jiang Yazhuo, Liang Liang, Wu Jinpeng, Cao Lin, Zhou Xiaoman, Song Zhihui, Ye Zhenyu, Zhao Ziyan, Feng Hui. Dysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/miR-1-3p axis in bladder cancer [J]. Journal of Experimental & Clinical Cancer Research, 2022, 41(1): 228.

[16] Fu Shijie, Dang Yanting, Xu Huilin, Li Aimin, Zhou Xiaoman, Gao Xiaodong, Li Zijie. Aloe vera-fermented beverage ameliorates obesity and gut dysbiosis in high-fat-diet mice [J]. Foods, 2022, 11(22): 3728.

[17] Zhao Xinyue, Ning Lulu, Zhou Xiaoman, Song Zhihui, Zhang Jianjian, Guan Feng, Yang Xiao-Feng. An activatable near-infrared fluorescence hydrogen sulfide (H2S) donor for imaging H2S release and inhibiting inflammation in cells [J]. Analytical Chemistry, 2021, 93(11): 4894-4901.

[18] Zhou Xiaoman, Zhang Jianjian, Song Zhihui, Lu Shuxian, Yu Yuan, Tian Jing, Li Xiang, Guan Feng. ExoTracker: a low-pH-activatable fluorescent probe for labeling exosomes and monitoring endocytosis and trafficking [J]. Chemical communications, 2020, 56(94): 14869-14872.

[19] Zhou Xiaoman, Zhai Yanhong, Liu Changmei, Yang Ganglong, Guo Jia, Li Guang, Sun Chengwen, Qi Xiaowei, Li Xiang, Guan Feng. Sialidase NEU1 suppresses progression of human bladder cancer cells by inhibiting fibronectin-integrin α5β1 interaction and Akt signaling pathway [J]. Cell Communication and Signaling, 2020, 18: 1-15.

[20] Zhou Xiaoman, Yang Ganglong, Guan Feng. Biological functions and analytical strategies of sialic acids in tumor [J]. Cells, 2020, 9(2): 273.

[21] Tan Zengqi, Cao Lin, Wu Yurong, Wang Bowen, Song Zhihui, Yang Juhong, Cheng Lanming, Yang Xiaomin, Zhou Xiaoman, Dai Zhijun. Bisecting GlcNAc modification diminishes the pro‐metastatic functions of small extracellular vesicles from breast cancer cells [J]. Journal of extracellular vesicles, 2020, 10(1): e12005.

[22] Zhou Xiaoman, Yang Shang, Yang Ganglong, Tan Zengqi, Guan Feng. Two-step derivatization and mass spectral distinction of α2, 3 and α2, 6 sialic acid linkages on N-glycans by MALDI-TOF [J]. Chinese Chemical Letters, 2019, 30(3): 676-680.

[23] Ma Minxing, Fu Yutong, Zhou Xiaoman, Guan Feng, Wang Yi, Li Xiang. Functional roles of fucosylated and O-glycosylated cadherins during carcinogenesis and metastasis [J]. Cellular Signalling, 2019, 63: 109365.

[24] Guo Jia, Liu Changmei, Zhou Xiaoman, Xu Xiaoqiang, Deng Linhong, Li Xiang, Guan Feng. Conditioned medium from malignant breast cancer cells induces an EMT-like phenotype and an altered N-glycan profile in normal epithelial MCF10A cells [J]. International Journal of Molecular Sciences, 2017, 18(8): 1528.

[25] Lu Xinyao, Wang Guangsheng, Feng Yue, Liu Song, Zhou Xiaoman, Du Guocheng, Chen Jian. The N-terminal α-helix domain of Pseudomonas aeruginosa lipoxygenase is required for its soluble expression in Escherichia coli but not for catalysis [J]. Journal of Microbiology and Biotechnology, 2016, 26(10): 1701-1707.

[26] Lu Xinyao, Liu Song, Feng Yue, Rao Shengqi, Zhou Xiaoman, Wang Miao, Du Guocheng, Chen Jian. Enhanced thermal stability of Pseudomonas aeruginosa lipoxygenase through modification of two highly flexible regions [J]. Applied microbiology and biotechnology, 2014, 98: 1663-1669.

[27] Lu Xinyao, Liu Song, Zhang Dongxu, Zhou Xiaoman, Wang Miao, Liu Yi, Wu Jing, Du Guocheng, Chen Jian. Enhanced thermal stability and specific activity of Pseudomonas aeruginosa lipoxygenase by fusing with self-assembling amphipathic peptides [J]. Applied microbiology and biotechnology, 2013, 97: 9419-9427.